KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPN18
All Species:
22.42
Human Site:
T48
Identified Species:
54.81
UniProt:
Q99952
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99952
NP_055184.2
460
50482
T48
K
A
D
G
V
C
S
T
V
A
G
S
R
P
E
Chimpanzee
Pan troglodytes
XP_513663
807
91678
T46
K
A
D
K
T
Y
P
T
T
V
A
E
K
P
K
Rhesus Macaque
Macaca mulatta
XP_001093333
456
50339
T48
K
A
D
G
M
C
S
T
K
A
G
S
R
P
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q61152
453
50183
T48
K
S
E
G
V
C
S
T
K
A
G
S
R
L
G
Rat
Rattus norvegicus
NP_001013129
453
50088
T48
K
T
E
G
V
C
S
T
K
A
G
S
Q
Q
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521024
682
72925
S107
A
G
G
G
S
C
G
S
K
K
G
R
A
G
R
Chicken
Gallus gallus
XP_001235234
775
85980
T46
R
S
D
K
I
Y
P
T
V
T
A
E
C
P
E
Frog
Xenopus laevis
NP_001121240
511
57423
T47
A
F
R
N
D
Y
T
T
E
V
G
A
S
Q
E
Zebra Danio
Brachydanio rerio
NP_001013470
513
57261
T48
K
E
D
Y
G
L
T
T
N
A
G
G
M
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796904
967
106580
T52
R
T
E
K
V
Y
P
T
S
A
G
E
S
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.1
94.7
N.A.
N.A.
75.8
74.7
N.A.
36.5
27.6
42.2
39.1
N.A.
N.A.
N.A.
N.A.
22.6
Protein Similarity:
100
38.7
96.5
N.A.
N.A.
82.6
82.3
N.A.
46.9
40.6
58.7
55.3
N.A.
N.A.
N.A.
N.A.
32.4
P-Site Identity:
100
33.3
86.6
N.A.
N.A.
66.6
60
N.A.
20
33.3
20
40
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
46.6
93.3
N.A.
N.A.
80
73.3
N.A.
26.6
53.3
33.3
46.6
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
30
0
0
0
0
0
0
0
60
20
10
10
0
0
% A
% Cys:
0
0
0
0
0
50
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
50
0
10
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
0
10
30
0
0
0
0
0
10
0
0
30
0
0
50
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
10
50
10
0
10
0
0
0
80
10
0
10
20
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
60
0
0
30
0
0
0
0
40
10
0
0
10
10
10
% K
% Leu:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
30
0
0
0
0
0
0
40
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
10
20
0
% Q
% Arg:
20
0
10
0
0
0
0
0
0
0
0
10
30
0
10
% R
% Ser:
0
20
0
0
10
0
40
10
10
0
0
40
20
0
0
% S
% Thr:
0
20
0
0
10
0
20
90
10
10
0
0
0
0
0
% T
% Val:
0
0
0
0
40
0
0
0
20
20
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
40
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _